医療関係資格試験マニア

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解説

 

Ａ  Chewing tobacco
B  Implantation of amalgam
C  Lead poisoning 
D  Melanoma 
E  Peutz-Jegher's syndrome
 

解答： D

The presence of an asymmetric lesion with irregular borders
and colors is most consistent with melanoma.
Histopathological examination revealed an infiltrating lentiginous melanoma in this case. 


 
An otherwise healthy 45-year-old man presented with a 4-week history of nonpainful discoloration of the maxillary gingiva.
He had no history of pigmented skin lesions.
Intraoral examination showed areas of the gingiva that were black.
The lesion was a pigmented macule, 1.5 cm by 4 cm in greatest dimension, with asymmetric and irregular borders and colors.
Histopathological examination revealed an infiltrating lentiginous melanoma.
Oral melanoma is a rare neoplasm.
Exposure to the sun is clearly linked to cutaneous melanoma but is not clearly associated with oral melanoma.
The patient underwent partial maxillectomy with 2-cm margins, but he declined adjuvant radiotherapy and chemotherapy.
No pathologic lymph nodes were found.
At follow-up 6 months after surgery, there were no signs of tumor recurrence.

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